Epigenetika

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.