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Institut za biološka istraživanja „Siniša Stanković”
Institut od nacionalnog značaja za Republiku Srbiju
Univerzitet u Beogradu

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Variation in thermal plasticity of larval morphology among crested newt species and their reciprocal hybrids (Salamandridae: Triturus)

Phenotypic plasticity is assumed to play crucial role under climate change, as it enables organisms to cope with rapidly increasing environmental pressures. We investigated the effect of water temperature on head and tail morphology in larvae of two crested newt species (Triturus ivanbureschi and T. macedonicus) and their reciprocal F1 hybrids. Larvae were raised under experimental conditions at 19 °C and, from the late larval phase (stage 62), were exposed to either 19 °C or 24 °C...

Indications that the direct effects of supplemented vitamin D3 on the adrenal cortex are of secondary importance...

Vitamin D3 supplementation is beneficial for various symptoms of aging and may stabilize hypothalamic-pituitary-adrenal (HPA) axis function. Systemic and local metabolic activation of vitamin D3 are essential for its acquisition of physiological activity and subsequent direct action. We reasonably believe that the direct effect of the active metabolite of vitamin D3 on the adrenal cortex is of secondary importance for glucocorticoid output, compared to the indirect, pituitary-mediated mechanism of its...

Activation of Intestinal Type 3 Innate Lymphoid Cells and Regulatory T Cells Through Free Fatty Acid Receptor 2 Ameliorates...

Reduction in intestinal type 3 innate lymphoid cells (ILC3) frequency is associated with type 1 diabetes (T1D) pathogenesis in humans and in animal models. The current study showed that, after T1D induction by multiple–low-dose streptozotocin in male C57BL/6 mice, ILC3 were reduced in both blood and pancreas and produced less IL-22 and IL-2, and a decreased proportion expressed the gut-homing α4β7 integrin in the pancreas. Additionally, T1D induction in ILC3-impaired...

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